ABSTRACT
Objective To evaluate the safety and feasibility of early feeding in children after orthopaedic surgery.Methods Totally 638 children with general anesthesia after orthopaedic surgery in a tertiary hospital in Beijing were recruited and divided into two groups.Children in the experimental group (n=315) started water drinking and feeding if they passed the postoperative assessment on consciousness and digestive function,while children in the control group (n=323) adhered to the conventional protocol of 6h fasting postoperatively.Results The average initial time of water drinking,liquid food feeding and general diet in the experimental group were 0.63 h,1.03 h and 3.07 h,while they were 6.42 h,6.88 h and 8.79 h in the control group,and the differences were statistically significant (P＜0.001).There were no significant differences in the incidence,severity and frequency of postoperative nausea and vomiting between two groups in 6h and 24h after returning to wards(P＞0.05).At 6h after returning to wards,the incidences of moderate-to-severe thirst and hunger in the experimental group were significantly lower than those in the control group(P＜0.001),and pain scored over 3 marks was lower than the control group(P=0.002).Conclusion Children after orthopaedic surgery with general anesthesia are likely to drink water 1 h after returning to wards and then take general diet 2h later while comprehensive prevention measures being adopted.Early teeding would not aggravate postoperative nausea and voniting and can alleviate the extent of postoperative thirst,hunger and pain.
ABSTRACT
Objective To investigate the effect of Naloxone in the pre-hospital care of AOPP.Methods 54 patients with the pre-hospital care of AOPP were divideded into two groups.The treatment group was treated with Naloxone,Atropine and Pyridine aldoxime methyliodide,the control group treated with Atropine and Pyridine aldoxime methyliodide,and the results were analyzed using t-test and x2 test.The efficacy of the two groupswas compareded.Results In the treatment group,the mumber of drug delivery and the dosage of Atropine were less.The recovery time of the actirity of Cholinesterase and the patients coma were shorter.Complications and mortality was significantly lower,but the cure rate was significantly higher than that of the control group.Conclusion Naloxone is effective and safe in the treatment the pre-hospital care of AOPP.It is worthy of clinical promotion.
ABSTRACT
Objective To explore the differences and similarities of clinical characteristics,pathological features, treatment and prognosis between primary gastric lymphoma(PGL)and primary intestinal lymphoma (PIL). Methods The clinical characteristics, pathological features, therapeutic results, the detection of Helicobacter pylori (Hp) and prognosis of 48 PGL cases and 15 PIL cases were retrospectively analyzed. Results There was no statistical significance in age, gender, abdominal pain, gastrointestinal bleeding, B symptoms, clinical stage, mortality between PGL and PIL groups (P>0. 05). However, there were significant differences in the pathological type, acute abdomen emergency surgery between these two groups (P<0. 05). There was 12 Hp positive cases in mucosalassociated lymphoid tissue (MALT) lymphoma of PGL group (12/19), and 5 Hp positive cases in diffuse large B-cell lymphoma (DLBCL) (5/20). There was significant difference in Hp detection rate of these two pathological types. Hp was not found in PIL group. The Cox multivariate analysis indicated that stage Ⅲ-Ⅳ was the independent adverse factors affecting PGL prognosis (P<0. 05).Conclusions Mainly histological types are DLBCL and MALT lymphoma in PGL, and DLBCL in PIL.PIL predispose to T-cell lymphoma compared with PGL. MALT lymphoma is rare in PIL group. The mainly clinical stage is Ⅲ-Ⅳ both in PGL group and PIL group. Emergency surgery is often needed in PIL because of intussusception or perforation. The prognosis of PGL is correlated with the stage and the prognosis of PIL are correlated with the stage, B symptoms and T cell phenotype.